IIT Guwahati developed approach for making sugar substitute “Xylitol”


Researchers at IIT Guwahati have created a fermentation course of that makes use of ultrasound to soundly generate Xylitol from sugarcane bagasse, the byproduct of crushing sugar cane. This strategy will get over the operational constraints of chemical synthesis and the time lags of conventional fermentation. The usage of ultrasound throughout the fermentation course of not solely decreased the time of fermentation to fifteen hours, but additionally elevated the yield of the product by nearly 20%

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Xylitol: Requirement for Secure Sweetners

  • There was a rise in using secure different sweeteners as consciousness of the destructive results of white sugar (sucrose) on people with diabetes and basic well being has grown.
  • A sugar alcohol generated from crops known as xylitol could have anti-obesogenic and anti-diabetic properties along with being a gentle prebiotic and guarding tooth in opposition to caries.

Xylitol: Analysis Staff

  • The analysis staff contains Dr. Belachew Zegale Tizazu and Dr. Kuldeep Roy, who co-authored the analysis articles, and was headed by Professor VS Moholkar of the Division of Chemical Engineering at IIT Guwahati.
  • Two peer-reviewed publications, Bioresource Expertise and Ultrasonics Sonochemistry, each revealed this analysis.
  • Benefits of this new process: The usage of ultrasound throughout the fermentation course of not solely decreased the time of fermentation to fifteen hours (versus nearly 48 hours in typical processes), but additionally elevated the yield of the product by nearly 20%, in response to Professor VS Moholkar, Division of Chemical Engineering, IIT Guwahati.

Xylitol: Resolving Present Sugar Substitute Drawback

  • With a purpose to create xylitol industrially, D-xylose, a dear chemical derived from wooden, is processed with nickel catalyst at extraordinarily excessive temperatures and pressures, which makes the method exceedingly energy-intensive.
  • Solely 8–15% of xylose is transformed to xylitol, and the method includes quite a few separation and purification steps, all of which translate to a excessive price for the consumer.
  • An interesting organic methodology to deal with these issues is fermentation. The method of fermentation just isn’t new. Fermentation is the method utilized in many Indian households to show milk into curd.
  • In fermentation, many sorts of microbes, together with micro organism and yeast, are used to alter one materials into one other.
  • The slowness of fermentation processes—the prolonged time it takes to show milk into curd, as an example—creates a major barrier to their use on a big scale in trade.
  • To resolve the aforementioned two points, the IIT Guwahati researchers employed two methods:
  • First, they employed sugarcane bagasse because the uncooked materials, which is the fibrous waste product left behind after extracting the sugarcane juice. This presents a strategy to upcycle a waste product and will get over the fee restrictions of the current xylitol synthesis strategies.
  • Second, they employed a novel fermentation approach wherein ultrasonic waves are used to hurry up the microbe-induced synthesis of xylitol.
  • The hemicellulose in bagasse was first hydrolyzed into 5 carbon (pentose) sugars like xylose and arabinose. They did this by chopping up the bagasse into tiny items and treating it with weak acid.
  • The sugar resolution was then concentrated, and fermentation was induced by including Candida tropicalis, a sort of yeast.

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